Adverse

1. In hostile opposition to; unfavorable; unpropitious; contrary to one's wishes; unfortunate; calamitous; afflictive; hurtful; as, adverse fates, adverse circumstances, things adverse.
2. Opposite.
3. To oppose; to resist.
4. Acting against, or in a contrary direction; opposed; contrary; opposite; conflicting; as, adverse winds; an adverse party; a spirit adverse to distinctions of caste.